Jane Bryden is a highly acclaimed and distinguished advocate of chamber music who has appeared with St. Luke's Chamber Ensemble, the Kennedy Center Chamber Players and Calliope. In addition, she is well known as a historically informed performer of Baroque music and collaborates with such period instrument ensembles as the Bach Ensemble, the Boston Museum Trio, Aston Magna, the Aulos Ensemble, the Santa Fe Pro Musica and the Smithsonian Chamber Orchestra. Bryden performed the role of Angelica in Peter Sellar's production of Handel's Orlando and is a founding member of Boston's Emmanuel Music, with whom she has given more than 100 performances of Bach cantatas in the liturgical context.

Bryden has also been a soloist with the New York Philharmonic, the Boston Symphony and the Baltimore Symphony. Other career highlights include touring Israel with Zubin Mehta and the Israel Philharmonic and premiering Andrew Imbrie's Requiem with the San Francisco Symphony, conducted by Edo de Waart. In the world premieres of Ronald Perera's operas The Yellow Wallpaper and S at Smith College, she created the roles of Charlotte and Sarah. Other composers whose works she has premiered include John Harbison, Earl Kim, Martin Boykan, Donald Sur and Donald Wheelock.

As a recipient of a Howard Foundation grant, Bryden produced and participated in a festival of the music of Luigi Dallapiccola. Her recent performances include the Mozart Requiem at Tanglewood with the Boston Early Music Festival Orchestra, Andrew Parrott directing (recorded for Denon), a series of Bach Cantata recordings for the BBC in London, the Brahms Liebeslieder Walzer for the Mark Morris Dance Company and solo recitals at the Hopkins Center and Carnegie Hall's Weill Recital Hall. Her recordings have been released on Koch International Classics, L'Oiseau Lyre, Pro Arte, Angel, Denon, CBS Masterworks, Deutsche Harmonia Mundi and CRI. A CD of Robert Schumann songs with fortepiano was released by Gasparo Records.