John E. Moore teaches a wide range of courses on aspects of European art and architecture from 1400 to 1800.

He has published an article on The Monument, a 202-foot Portland stone column designed and built (1671–77) by Sir Christopher Wren to commemorate the Great Fire of London; several articles and contributions to edited volumes on festivals (and related ephemeral designs) and printmaking in 18th-century Rome; and a study of the content, editorial development, publication and initial distribution of the Antichità d'Ercolano, lavishly illustrated volumes intimately connected not only to archaeology and art history, but also to statecraft and the career and interests of Bernardo Tanucci, the powerful and learned secretary of state in the kingdom of the Two Sicilies.

Moore's ongoing research projects explore, among other themes, relationships between the visual arts and the conduct of diplomacy in 18th-century Europe. His scholarly work has been supported by research fellowships in Rome (at the American Academy in Rome), Los Angeles (at the Getty Research Institute) and Wolfenbüttel (at the Herzog August Bibliothek).